The Sai Lab

Molecular architecture of the SARS-CoV-2 virus. https://doi.org/10.1101/2020.07.08.192104
Hangping Yao*, Yutong Song*, Yong Chen*, Nanping Wu*, Jialu Xu*, Chujie Sun, Jiaxing Zhang, Tianhao Weng, Zheyuan Zhang, Zhigang Wu, Linfang Cheng, Danrong Shi, Xiangyun Lu, Jianlin Lei, Max Crispin, Yigong Shi, Lanjuan Li#, and Sai Li#

High-Resolution Description of the Hantavirus Surface Glycoprotein Lattice and Its Membrane Fusion Control Mechanism.
Alexandra Serris, Robert Stass, Eduardo A. Bignon, Nicolas A. Muena, Jean-Claude Manuguerra, Rohit K. Jangra, Sai Li, Kartik Chandran, Nicole Tischler, Juha T. Huiskonen, Felix A. Rey, and Pablo Guardado-Calvo

PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins.
Ying Liu*, Yutong Song*, Siyu Zhang, Min Diao, Shanjin Huang, Sai Li, and Xu Tan

Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex.
Yanqing Zhang*, Sai Li*, Xuechen Zhu*, Gaoxingyu Huang*, Chao Zeng*, Qifan Wang, Kunpeng Wang, Qiang Zhou, Wusheng Zhang, Guangwen Yang, Minhao Liu, Qinghua Tao, Jianlin Lei, and Yigong Shi

Packaging and delivering enzymes by amorphous metal-organic frameworks.
Xiaoling Wu, Hua Yue, Yuanyu Zhang, Xiaoyong Gao, Xiaoyang Li, Licheng Wang, Yufei Cao, Miao Hou, Haixia An, Lin Zhang#, Sai Li#, Jingyuan Ma, He Lin, Yanan Fu, Hongkai Gu, Wenyong Lou, Wei Wei#, Richard N. Zare, Jun Ge#

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.
Kamel El Omari, Sai Li, Abhay Kotecha, Thomas S Walter, Eduardo Andres Bignon, Karl Harlos, Pentti Somerharju, Felix De Haas, Daniel K. Clare, Mika Molin, Felipe Hurtado, Mengqiu Li, Jonathan M. Grimes, Dennis H. Bamford, Nicole D. Tischler, Juha T. Huiskonen, David I. Stuart, Elina Roine

Heteromeric GABAA receptor structures in positively modulated active-states.
Paul Miller, Simonas Masiulis, Tomas Malinauskas, Abhay Kotecha, Shanlin Rao, Sreenivas Chavali, Luigi De Colibus, Els Pardon, Saad Hannan, Suzanne Scott, Zhaoyang Sun, Brandon Frenz, Gianni Kleese, Sai Li, Jonathan Diprose, Alistair Siebert, Robert Esnouf, Frank DiMaio, Stephen Tucker, Trevor Smart, Jan Steyaert, M. Madan Babu, Mark Sansom, Juha Huiskonen, Alexandru Aricescu

Structure of the Lassa virus glycan shield provides a model for immunological resistance.
Yasunori Watanabe, Jayna Raghwani, Joel D. Allen, Gemma E. Seabright, Sai Li, Felipe Moser, Juha T. Huiskonen, Thomas Strecker, Thomas A. Bowden, Max Crispin

Shielding and activation of a viral membrane fusion protein
Steinar Halldorsson*,Sai Li* , Mengqiu Li, Karl Harlos, Thomas A. Bowden, Juha T. Huiskonen

Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope
Ilona Rissanen, Robert Stass, Antra Zeltina, Sai Li, Jussi Hepojoki, Karl Harlos, Robert J. C. Gilbert, Juha T. Huiskonen, Thomas A. Bowden

A molecular-level account of the antigenic hantaviral surface.
Sai Li, Ilona Rissanen, Antra Zeltina, Jussi Hepojoki, Jayna Raghwani, Karl Harlos, Oliver G. Pybus, Juha T. Huiskonen, Thomas A. Bowden.

Acidic pH-induced conformations and LAMP1 binding of the Lassa virus glycoprotein spike.
Sai Li, Zhaoyang Sun, Rhys Pryce, Marie-Laure Parsy, Sarah K Fehling, Katrin Schlie, C Alistair Siebert, Wolfgang Garten, Thomas A Bowden, Thomas Strecker, Juha T Huiskonen

Averaging of Viral Envelope Glycoprotein Spikes from Electron Cryotomography Reconstructions using Jsubtomo.
Juha T Huiskonen, Marie-Laure Parsy, Sai Li, David Bitto, Max Renner, Thomas A Bowden

pH-Controlled Two-Step Uncoating of Influenza Virus.
Sai Li*, Christian Sieben*, Kai Ludwig, Chris T Höfer, Salvatore Chiantia, Andreas Herrmann, Frederic Eghiaian, Iwan A.T. Schaap

Super Hydrophobic PES Membrane and its Application in Biomedical Industry.
Eberhard Wuenn, Joerg Hosch, Sai Li, Iwan A.T. Schaap, Tobias Schleuss

Cell Visco-Elasticity Measured with AFM and Optical Trapping at Sub-Micrometer Deformations.
Schanila Nawaz, Paula Sánchez, Kai Bodensiek, Sai Li, Mikael Simons, Iwan A T Schaap

Critical Time Window of Neuronal Cholesterol Synthesis during Neurite Outgrowth.
Ursula Fünfschilling, Wolf J. Jockusch, Nandhini Sivakumar, Wiebke Möbius, Kristina Corthals, Sai Li, Susanne Quintes, Younghoon Kim, Iwan A. T. Schaap, Jeong-Seop Rhee, Klaus-Armin Nave, Gesine Saher

Bending and Puncturing the Influenza Lipid Envelope.
Sai Li, Frederic Eghiaian, Christian Sieben, Andreas Herrmann, Iwan A.T. Schaap

Femtosecond 5-W Yb:KGW slab laser oscillator pumped by a single broad-area diode and its application as supercontinuum source.
Felix Hoos, Todd Meyrath, Sai Li, Bernd Braun, and Harald Giessen

Highly efficient 4 W, 161 fs, Yb:KGW laser oscillator.
Felix Hoos, Todd Meyrath, Sai Li, Bernd Braun, and Harald Giessen

Efficient and Simple High-Power Femtosecond Yb:KGW Slab-Laser Pumped by a Single Broad-Area Emitter Diode.
Felix Hoos, Todd P. Meyrath, Sai Li, Bernd Braun, Harald Giessen