Journal Publications

36. Lanqing Luo; Junyao Li; Xueying Shen; Xinyan Li; Cheng Peng; Sai Li; Rui Kuai; A Bioinspired Nanovaccine for Personalized Cancer Immunotherapy, Nano Letters (online)

https://doi.org/10.1021/acs.nanolett.4c04557

35. Jinchao Yu; Xinyan Li; Junyao Li; Nan Sun; Cheng Peng; Jiayi Huang; Sai Li; Rui Kuai; Single-Dose Physically Cross-Linked Hyaluronic Acid and Lipid Hybrid Nanoparticles Containing Cyclic Guanosine Monophosphate–Adenosine Monophosphate Eliminate Established Tumors, ACS Nano (online)

DOI: https://doi.org/10.1021/acsnano.4c10673

34. Ye Hong#; Baoying Huang#; Junxia Zhang#; Cheng Peng; Weizheng Kong; Wenjie Tan*; Sai Li*; Molecular Architecture of Monkeypox Mature Virus, Cell Discovery, 2024, 10: 108 

DOI: https://doi.org/10.1038/s41421-024-00741-5

33. Jia He; Chaoyu Wang; Xiao Fang; Junyao Li; Xueying Shen; Junxia Zhang; Cheng Peng; Hongjian Li; Sai Li; Jeffrey M. Karp; Rui Kuai; Tuning the fluidity and protein corona of ultrasound-responsive liposomal nanovaccines to program T cell immunity in mice, Nature Communications, 2024, 15: 8121

DOI: https://doi.org/10.1038/s41467-024-52104-z

32. Maofei Chen#; Yutong Song#; Sensen Zhang#; Yitang Zhang#; Xudong Chen; Minghui Zhang; Meng Han; Xin Gao; Sai Li*; Maojun Yang*; Molecular architecture of mammalian pyruvate dehydrogenase complex, Protein & Cell, 2024, pwae044;

DOI: https://doi.org/10.1093/procel/pwae044

31. Junyao Li; Lanqing Luo; Jia He; Jinchao Yu; Xinyan Li; Xueying Shen; Junxia Zhang; Sai Li; Jeffrey M. Karp; Rui Kuai; A virus-inspired inhalable liponanogel induces potent antitumor immunity and regression in metastatic lung tumors, Cancer Research, 2024;

DOI: 10.1158/0008-5472.CAN-23-3414

30. Sai Li; Ming-Yuan Su; Long Li; Tiantian Cai; Zhe Zhang; Yanyan Li; A new generation of structural biologists in China, Structure, 2024, 32(3): 253-257;

DOI: https://doi.org/10.1016/j.str.2024.01.014

29. Chaoyu Wang; Ruoshi Zhang; Jia He; Lvshan Yu; Xinyan Li; Junxia Zhang; Sai Li; Conggang Zhang; Jonathan C. Kagan; Jeffrey M. Karp; Rui Kuai; Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity, Nature Communications, 2023, 14: 3877;

DOI: https://doi.org/10.1038/s41467-023-39607-x

28. Yutong Song#; Hangping Yao#; Nanping Wu#; Jialu Xu#; Zheyuan Zhang#; Cheng Peng; Shibo Li; Weizheng Kong; Yong Chen; Miaojin Zhu; Jiaqi Wang; Danrong Shi; Chongchong Zhao; Xiangyun Lu; Martín Echavarría Galindo; Sai Li; In situ architecture and membrane fusion of SARS-CoV-2 Delta variant, Proceedings of the National Academy of Sciences of the United States of America, 2023, 120(18): e2304603120;

DOI: 10.1073/pnas.2213332120

27. Dali Wang#; Jiaxuan Li#; Lei Wang; Yipeng Cao; Bo Kang; Xiangfei Meng; Sai Li*; Chen Song*; Toward Atomistic Models of Intact SARS-CoV-2 via Martini Coarse-Grained Molecular Dynamics Simulations, Quantitative Biology, 2023, 11(4): 421-433;

DOI: https://doi.org/10.1002/qub2.20

26. Ye Hong#; Yutong Song#; Zheyuan Zhang; Sai Li; Cryo-electron tomography: the resolution revolution and a surge of in situ virological discoveries, Annual Review of Biophysics, 2023, 52: 339-360; 

DOI: 10.1146/annurev-biophys-092022-100958

25. Julio Rey Ramirez; Peter Rautek; Ciril Bohak; Ondřej Strnad; Zheyuan Zhang; Sai Li; Ivan Viola; Wolfgang Heidrich; GPU Accelerated 3D Tomographic Reconstruction and Visualization from Noisy Electron Microscopy Tilt-Series, IEEE Transactions on Visualization and Computer Graphics, 2022: 1-15; 

DOI: 10.1109/TVCG.2022.3230445.

24. Ngan Nguyen#; Ciril Bohak#; Dominik Engel; Peter Mindek; Ondrej Strnad; Peter Wonka; Sai Li; Timo Ropinski; Ivan Viola; Finding Nano-Ötzi: Cryo-Electron Tomography Visualization Guided by Learned Segmentation, IEEE Transactions on Visualization and Computer Graphics, 2022, 29(10): 4198-4214;  

DOI: 10.1109/TVCG.2022.3186146

23. Sai Li; Cryo-electron tomography of enveloped viruses, Trends in Biochemical Sciences, 2022, 47(2): 173-186; 

DOI: 10.1016/j.tibs.2021.08.005

22. Shulin Li; Rui Yan; Jialu Xu; Shiqun Zhao; Xinyu Ma; Qiming Sun; Min Zhang; Ying Li; Jun-Jie Gogo Liu; Liangyi Chen; Sai Li; Ke Xu; Liang Ge; A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis, Cell Research, 2022, 32(2): 119-138; 

DOI: 10.1038/s41422-021-00563-0

21. Joel D. Allen; Himanshi Chawla; Firdaus Samsudin; Lorena Zuzic; Aishwary Tukaram Shivgan; Yasunori Watanabe; Wan-ting He; Sean Callaghan; Ge Song; Peter Yong; Philip Brouwer; Yutong Song; Yongfei Cai; Helen M. E. Duyvesteyn; Tomas Malinauskas; Joeri Kint; Paco Pino; Maria J. Wurm; Martin Frank; Bing Chen; David I. Stuart; Rogier W. Sanders; Raiees Andrabi; Dennis R. Burton; Sai Li; Peter J. Bond*; Max Crispin*; Site-specific steric control of SARS-CoV-2 spike glycosylation, Biochemistry, 2021, 60(27): 2153-2169;

DOI: 10.1021/acs.biochem.1c00279

Cover story

20. Xiaohui Ju; Yunkai Zhu; Yuyan Wang; Jingrui Li; Jiaxing Zhang; Mingli Gong; Wenlin Ren; Sai Li; Jin Zhong; Qiangfeng Cliff Zhang; Rong Zhang; Qiang Ding; A novel cell culture system modeling the SARS-CoV-2 life cycle, PLoS Pathogens, 2021, 17(3): e1009439; 

DOI: 10.1371/journal.ppat.1009439

19. Hangping Yao#; Yutong Song#; Yong Chen#; Nanping Wu#; Jialu Xu#; Chujie Sun; Jiaxing Zhang; Tianhao Weng; Zheyuan Zhang; Zhigang Wu; Linfang Cheng; Danrong Shi; Xiangyun Lu; Jianlin Lei; Max Crispin; Yigong Shi; Lanjuan Li*; Sai Li*; Molecular architecture of the SARS-CoV-2 virus, Cell, 2020 183(3): 730-738; 

DOI: 10.1016/j.cell.2020.09.018

F1000 recommended

ESI Hot Paper

Reported on the New York Times front page, October 9th, 2020

18. Alexandra Serris; Robert Stass; Eduardo A. Bignon; Nicolas A. Muena; Jean-Claude Manuguerra; Rohit K. Jangra; Sai Li; Kartik Chandran; Nicole Tischler; Juha T. Huiskonen; Felix A. Rey*; Pablo Guardado-Calvo*; The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism, Cell, 2020, 183(2): 442-456; 

DOI: 10.1016/j.cell.2020.08.023

17. Ying Liu#; Yutong Song#; Siyu Zhang; Min Diao; Shanjin Huang; Sai Li; Xu Tan; PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins, Cell Discovery, 2020, 6(1): 53; 

DOI: 10.1038/s41421-020-0184-9

16. Yanqing Zhang#; Sai Li#; Xuechen Zhu#; Gaoxingyu Huang#; Chao Zeng#; Qifan Wang; Kunpeng Wang; Qiang Zhou; Wusheng Zhang; Guangwen Yang; Minhao Liu; Qinghua Tao; Jianlin Lei; Yigong Shi; Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex, Cell Research, 2020, 30(6): 532-540;

DOI: 10.1038/s41422-020-0320-y

F1000 recommended, Cover story

15. Xiaoling Wu; Hua Yue; Yuanyu Zhang; Xiaoyong Gao; Xiaoyang Li; Licheng Wang; Yufei Cao; Miao Hou; Haixia An; Lin Zhang*; Sai Li*; Jingyuan Ma; He Lin; Yanan Fu; Hongkai Gu; Wenyong Lou; Wei Wei*; Richard N. Zare; Jun Ge*; Packaging and delivering enzymes by amorphous metal-organic frameworks, Nature Communications, 2019, 10(1): 5165;

DOI: 10.1038/s41467-019-13153-x

14. Kamel El Omari; Sai Li; Abhay Kotecha; Thomas S Walter; Eduardo Andres Bignon; Karl Harlos; Pentti Somerharju; Felix De Haas; Daniel K. Clare; Mika Molin; Felipe Hurtado; Mengqiu Li; Jonathan M. Grimes; Dennis H. Bamford; Nicole D. Tischler; Juha T. Huiskonen; David I. Stuart; Elina Roine; The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins, Nature Communications, 2019, 10(1): 846; 

DOI: 10.1038/s41467-019-08728-7

13. Yasunori Watanabe; Jayna Raghwani; Joel D. Allen; Gemma E. Seabright; Sai Li; Felipe Moser; Juha T. Huiskonen; Thomas Strecker; Thomas A. Bowden; Max Crispin; Structure of the Lassa virus glycan shield provides a model for immunological resistance, Proceedings of the National Academy of Sciences of the United States of America, 2018, 115(28): 7320-7325; 

DOI: 10.1073/pnas.1803990115

12. Steinar Halldorsson#; Sai Li#; Mengqiu Li; Karl Harlos; Thomas A. Bowden; Juha T. Huiskonen; Shielding and activation of a viral membrane fusion protein, Nature Communications, 2018, 9(1): 349; 

DOI: 10.1038/s41467-017-02789-2

11. Ilona Rissanen; Robert Stass; Antra Zeltina; Sai Li; Jussi Hepojoki; Karl Harlos; Robert J. C. Gilbert; Juha T. Huiskonen; Thomas A. Bowden; Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope, Journal of Virology, 2017, 91(21): e00378-17; 

DOI: 10.1128/JVI.00378-17

10. Sai Li; Ilona Rissanen; Antra Zeltina; Jussi Hepojoki; Jayna Raghwani; Karl Harlos; Oliver G. Pybus; Juha T. Huiskonen; Thomas A. Bowden; A Molecular-Level Account of the Antigenic Hantaviral Surface, Cell Reports, 2016, 15(5): 959-967; 

DOI: 10.1016/j.celrep.2016.06.039

9. Sai Li; Zhaoyang Sun; Rhys Pryce; Marie-Laure Parsy; Sarah K Fehling; Katrin Schlie; C Alistair Siebert; Wolfgang Garten; Thomas A Bowden; Thomas Strecker; Juha T Huiskonen; Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike, PLoS Pathogens, 2016, 12(2): e1005418; 

DOI: 10.1371/journal.ppat.1005418

8. Juha T Huiskonen; Marie-Laure Parsy; Sai Li; David Bitto; Max Renner; Thomas A Bowden; Averaging of Viral Envelope Glycoprotein Spikes from Electron Cryotomography Reconstructions using Jsubtomo, Jove-Journal of Visualized Experiments, 2014, (92): e51714; 

DOI: 10.3791/51714

7. Sai Li#; Christian Sieben#; Kai Ludwig; Chris T Höfer; Salvatore Chiantia; Andreas Herrmann; Frederic Eghiaian, Iwan A.T. Schaap; pH-Controlled Two-Step Uncoating of Influenza Virus, Biophysical Journal, 2014, 106(7): 1447-56; 

DOI: 10.1016/j.bpj.2014.02.018

6. Eberhard Wuenn; Joerg Hosch; Sai Li; Iwan A.T. Schaap; Tobias Schleuss; Super Hydrophobic PES Membrane and its Application in Biomedical Industry, Procedia Engineering, 2012, 44: 449-450; 

DOI: 10.1016/j.proeng.2012.08.445

5. Schanila Nawaz; Paula Sánchez; Kai Bodensiek; Sai Li; Mikael Simons; Iwan A T Schaap; Cell Visco-Elasticity Measured with AFM and Optical Trapping at Sub-Micrometer Deformations, PLoS One, 2012, 7(9): e45297; 

DOI: 10.1371/journal.pone.0045297

4. Ursula Fünfschilling; Wolf J. Jockusch; Nandhini Sivakumar; Wiebke Möbius; Kristina Corthals; Sai Li; Susanne Quintes; Younghoon Kim; Iwan A. T. Schaap; Jeong-Seop Rhee; Klaus-Armin Nave; Gesine Saher; Critical Time Window of Neuronal Cholesterol Synthesis during Neurite Outgrowth, Journal of Neuroscience, 2012, 32(22): 7632-45; 

DOI: 10.1523/JNEUROSCI.1352-11.2012

3. Sai Li; Frederic Eghiaian; Christian Sieben; Andreas Herrmann; Iwan A.T. Schaap; Bending and Puncturing the Influenza Lipid Envelope, Biophysical Journal, 2011, 100(3): 637-645; 

DOI: 10.1016/j.bpj.2010.12.3701

2. Felix Hoos; Todd Meyrath; Sai Li; Bernd Braun; Harald Giessen; Femtosecond 5-W Yb:KGW slab laser oscillator pumped by a single broad-area diode and its application as supercontinuum source, Applied Physics B: Lasers and Optics, 2009, 96(1): 5-10; 

DOI: 10.1007/s00340-009-3421-3

1. Felix Hoos; Sai Li; Todd Meyrath; Bernd Braun; Harald Giessen; Thermal lensing in an end-pumped Yb:KGW slab laser with high power single emitter diodes, Optics Express, 2008, 16(9): 6041-9; 

DOI: 10.1364/oe.16.006041

Publication in Chinese & Preprints & Under review/revision

4. Dongyang Dong#; Yutong Song#; Shipo Wu; Busen Wang; Cheng Peng; Weizheng Kong; Zheyuan Zhang; Li-Hua Hou; Sai Li; Molecular basis of Ad5-nCoV Vaccine-Induced Immunogenicity, bioRxiv, 2024;

DOI: 10.1101/2024.06.21.600005

3. 陈勇#; 张俊霞#; 江轶; 李赛 (2021). 新冠病毒感染机制的透射电镜研究评述. 实验技术与管理 38, 1-9. 

DOI: 10.16791/j.cnki.sjg.2021.12.001

2. 张佳星; 陈勇; 李赛 (2020). 冷冻电镜断层成像技术破解重构新冠病毒全分子结构难题. 电子显微学报 39, 787-789.

DOI: 10.3969/j.issn.1000-6281.2020.06.021

1. Paul Miller; Simonas Masiulis; Tomas Malinauskas; Abhay Kotecha; Shanlin Rao; Sreenivas Chavali; Luigi De Colibus; Els Pardon; Saad Hannan; Suzanne Scott; Zhaoyang Sun; Brandon Frenz; Gianni Kleese; Sai Li; Jonathan Diprose; Alistair Siebert; Robert Esnouf; Frank DiMaio; Stephen Tucker; Trevor Smart; Jan Steyaert; M. Madan Babu; Mark Sansom; Juha Huiskonen; Alexandru Aricescu; Heteromeric GABAA receptor structures in positively modulated active-states, bioRxiv, 2019;

DOI: https://www.biorxiv.org/content/10.1101/338343v2

Conferences

4. 2021 | SIGGRAPH '21: ACM SIGGRAPH 2021 Computer Animation Festival

What does a virus actually look like?

Peter Mindek; Ivan Viola; Ondrej Strnad; Ciril Bohak; Sai Li; Tobias Klein; Pages 1

DOI: 10.1145/3446562.3458551

3. 2010 | Biophysical Journal - BIOPHYS J

Mechanics of Lipid Bilayers of High Curvature.

Sai Li; Frederic Eghiaian; Iwan A. T. Schaap; 98(3):592a-593a

DOI: 10.1016/j.bpj.2009.12.3224

2. 2009 | Lasers and Electro-Optics 2009 and the European Quantum Electronics Conference.

CLEO Europe - EQEC 2009.

Highly efficient 4 W, 161 fs, Yb:KGW laser oscillator.

Felix Hoos; Todd Meyrath; Sai Li; Bernd Braun; Harald Giessen; Page CA7_3

DOI: 10.1109/CLEOE-EQEC.2009.5194645

1. 2009 | Advanced Solid-State Photonics

Efficient and Simple High-Power Femtosecond Yb:KGW Slab-Laser Pumped by a Single Broad-Area Emitter Diode.

Felix Hoos; Todd Meyrath; Sai Li; Bernd Braun; Harald Giessen; Page MB13

DOI: 10.1364/ASSP.2009.MB13